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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKB
All Species:
22.73
Human Site:
S309
Identified Species:
35.71
UniProt:
P12277
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12277
NP_001814.2
381
42644
S309
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Chimpanzee
Pan troglodytes
XP_510185
464
51502
S392
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
S309
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Dog
Lupus familis
XP_537561
394
44036
P322
L
G
K
H
E
K
F
P
E
V
L
K
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q04447
381
42695
S309
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Rat
Rattus norvegicus
P07335
381
42707
S309
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
N283
G
G
V
F
D
I
S
N
A
D
R
L
G
F
S
Chicken
Gallus gallus
P05122
381
42852
G309
L
G
K
H
E
K
F
G
E
V
L
K
R
L
R
Frog
Xenopus laevis
NP_001080363
376
42223
G304
L
S
K
N
D
K
F
G
E
I
L
K
R
L
R
Zebra Danio
Brachydanio rerio
NP_775329
381
42865
G309
V
S
K
H
E
K
F
G
E
I
L
K
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
E298
A
S
N
K
A
K
L
E
E
V
A
A
K
Y
N
Honey Bee
Apis mellifera
O61367
355
39990
E297
A
A
N
R
A
K
L
E
E
I
A
G
K
F
N
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
K301
I
S
A
K
D
D
F
K
K
I
C
S
D
M
K
Sea Urchin
Strong. purpuratus
P18294
1174
130851
D1097
L
S
Q
Q
K
I
F
D
S
I
L
D
H
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
S309
L
G
K
H
E
K
F
S
E
V
L
K
R
L
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
99.2
94.4
N.A.
96.5
96.5
N.A.
77.9
90.5
83.1
85.8
N.A.
42.7
40.9
37.7
22.4
Protein Similarity:
100
82.1
100
95.9
N.A.
98.6
98.4
N.A.
83.7
96.3
92.3
93.1
N.A.
59
58.7
55.9
28.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
93.3
66.6
73.3
N.A.
20
13.3
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
93.3
86.6
86.6
N.A.
26.6
26.6
46.6
53.3
Percent
Protein Identity:
N.A.
96.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
14
0
0
0
7
0
14
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
20
7
0
7
0
7
0
7
7
0
0
% D
% Glu:
0
0
0
0
60
0
0
14
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
80
0
0
0
0
0
0
14
0
% F
% Gly:
7
60
0
0
0
0
0
20
0
0
0
7
7
0
0
% G
% His:
0
0
0
60
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
0
0
0
14
0
0
0
34
0
0
0
0
0
% I
% Lys:
0
0
67
14
7
80
0
7
7
0
0
67
14
0
7
% K
% Leu:
67
0
0
0
0
0
14
0
0
0
74
7
0
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% M
% Asn:
0
0
14
7
0
0
0
7
0
0
0
0
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
7
0
67
0
74
% R
% Ser:
0
34
0
0
0
0
7
40
7
0
0
7
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
7
0
0
0
0
0
0
60
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _